...胞是具有自我更新和多向分化等特性的中枢原始细胞[1],常取自于胚胎组织和成年动物的室下区和海马齿状回[2]。神经球(neurosphere)是神经干细胞体外培养于含有丝分裂原组织培养液中表现出的一般形式,该悬浮球状细胞团中的细胞被认为保持了神经干细胞的基本增殖和...
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Large necrotic core will greatly reduce the expansion of NSCs. Therefore,it is important to simulate the dynamic process of the growth of neurospheres and analyze the critical size of the neurosphere at which the necrotic core appears.
因此,模拟神经球的动态生长过程并分析出现坏死细胞的临界神经球尺度对于神经干细胞的大规模扩增有重要意义。
参考来源 - 神经干细胞球生长动力学模型·2,447,543篇论文数据，部分数据来源于NoteExpress
对神经球行免疫荧光染色鉴定。
Immunofluorescence staining was performed to identify the neural stem cells.
目的研究神经球在形成过程中是否能结合异种细胞，并与之形成杂合细胞球。
Objective To investigate whether the neurospheres can merge with other cells and form heter-cell spheres during the process of neurospheres forming.
结果在神经球细胞中三种多巴胺受体均有表达，中脑与海马来源的神经球细胞无显著差异。
Results All three subtypes of dopamine receptors were expressed in neurospheres both from mesencephalon and from hippocampus.
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