该组合物可避免双胍类药物与磺酰脲药物的相互作用，提高组合物的治疗效果和稳定性。

The composite can avoid the interaction of biguanide medicine and sulfonylurea medicine and improves the treatment effect and the stability of the composite.

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所有患者在罗马Day Hospital of Metabolic Diseases接受BPD或常规药物治疗(即单独应用二甲双胍或与磺酰脲及胰岛素联合应用)。

All were treated at the Day Hospital of Metabolic Diseases in Rome with BPD or conventional medical therapy (i. e., metformin alone or with sulfonylurea or insulin).

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