带磁性颗粒的抗体要是没有与样本产生结合,会在溶液中快速旋转,因而无法产生磁性讯号。
Labeled antibodies that have not docked to the sample tumble about so rapidly in solution that they give off no magnetic signal.
方法:以同位素标记的单克隆抗体和微球的结合率为指标。用均匀设计法研究影响免疫磁性微球构建的因素。
Methods: What determines the binding percent of monoclonal antibodies to make magnetic beads is studied by uniform design methods, isotope marked antibody's binding percent as the criteria.
与样本结合的抗体则不能够旋转,它们的磁性标签也就协同一致地发出可以侦测到的磁场。
Bound antibodies, however, are unable to rotate, and together their magnetic tags generate a readily detectable magnetic field.
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