各国在文化上的不同和病人的差异影响了该病的干预效果。
The existence of cross-cultural differences and heterogeneity of patients in each country may influence the outcome of interventions for CLBP.
从总体上看,研究人员并未发现这四组病人之间有重大差异,但没有服用药片的病人的感冒病程略长、病情也略为严重。
Overall, researchers didn't find major differences between the four groups, but the length and severity of colds was slightly worse among patients who didn't receive pills.
另外,替代观察结局和病人结局之间的差异也是一个比较微妙的问题。
Another, subtler problem can be the difference between what are known as surrogate outcomes and patient outcomes.
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