...疏水性药物；新剂型 中图分类号：R943.4 文献标志码：A 文章编号：1007-7693(2011)04-0315-05 [gap=1232]KEY WORDS: poloxamers; hydrophobic drugs; new dosage forms ...
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The drug contents and loading efficiency of the micelles were investigated with UV spectrophotometry. The result showed that loading efficiency of the micelles for hydrophobic drug was good.
用紫外分光光度法测定胶束的载药量和包封率表明,共聚物胶束对疏水性药物的包载较好。
参考来源 - 叶酸受体靶向的聚乳酸共聚物胶束的制备及性质研究·2,447,543篇论文数据，部分数据来源于NoteExpress
提 高了纳米粒子的载药量及包封率，控制了疏水性药物的突释现象。
The invention improves the carrier and packing rate of nanometer particles, and controls the instant release condition of hydrophobic drug.
利用非微粒脂质给药系统，药物不必经过溶出的步骤，从而可以显著的提高疏水性药物的口服吸收。
Oral absorption of hydrophobic drugs can be significantly improved using lipid-based non-particulate drug delivery systems, which avoid the dissolution step.
本发明制备工艺简单，所 得纳米粒子粒径均匀，粒度分布较窄，对疏水性药物有较高的载药量和包封率。
The invention has simple process, uniform grain diameter, narrow graininess distribution, high carrier and packing rate on hydrophobic drug.
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