能够测试出亚纳米级生物膜厚度的增加量。
Thickness increase of bio-layer of angstrom level can be detected.
结果：高龋组变形链球菌临床分离株的生物膜厚度和细菌分布密度显著高于无龋组（P<0.05）；
RESULTS:The biofilm thickness and bacterial density in caries-active group were significantly higher than that in caries-free group (P<0.05);
根据活性生物膜扩张原理，建立了硝化生物膜中微生物相互作用的非稳态解析数学模型，并可预测生物膜厚度的变化与微生物菌群的空间分布。
Based on the principle of active biofilm expansion , a non-steady state analytic mathematical model of microbial interactions in nitrifying biofilm was developed.
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