考虑到其它试验中生活方式干预的强大效应，本研究的设计可能已经减少了那格列奈潜在利益的幅度。
Considering the powerful effects of lifestyle interventions in other trials, this design feature may have reduced the magnitude of the potential benefit from nateglinide.
世界范围内进行了多项大型预防糖尿病的临床试验，主要分为生活方式干预和药物干预两大类。
Multiple large clinical trials of preventing diabetes mellitus in the world were performed, which mainly assigned into life style intervention and drug intervention.
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