世界正面临着人口增长，同时供给和生产又被气候变化、供水保障和技术缺乏等因素限制着，特别是对于小农来说。

The world is confronting population growth, while supply and production is constrained by climate change, water scarcity and lack of technology, especially among smallholder farmers.

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就神经氨酸酶抑制剂而言，有一些重大的限制因素，主要是生产能力有限，同时，在许多国家，其价格高得难以负担。

For the neuraminidase inhibitors, the main constraints - which are substantial - involve limited production capacity and a price that is prohibitively high for many countries.

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不可预见性也是限制各公司和各国从事多种高附加值生产的一个主要因素。

Unpredictability is also a major constraint for companies and countries trying to diversify into higher value production.

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