灵菌红素(Prodigiosin,正式名称为2-methyl-3-pentyl-6-methoxyprodiginine)是Prodiginin(中文名不详)的一种。它具有Prodiginin的基本结构,也就是三吡咯环,其中的一个吡咯环C2上带有一个甲基,C3上则有一个戊基。灵菌红素是一种红色物质,可由粘质沙雷氏菌(Serratia marcescens)等细菌合成的次级代谢产物(secondary metabolite)。
The acute and the chronic toxicity of prodigiosin in mice was observed.
观察动物口服灵菌红素的急性毒性和长期毒性反应。
参考来源 - 新疆块根芍药(Paeonia anomala)内生菌的分离、XJUBy the study of the characters, it was found that the prodigiosin was photosensitive, not temperature-sensitive. It was more stable at solid state than at liquid state.
对其不同存在状态下的稳定性研究发现,灵菌红素对温度稳定,对光敏感,且固态比液态稳定,固态避光条件下则稳定性最高。
参考来源 - 灵菌红素生物合成与分离纯化研究·2,447,543篇论文数据,部分数据来源于NoteExpress
灵菌红素是由若干种细菌特别是粘质沙雷菌产生的一种红色吡咯色素。
Prodigiosin is an intensely red pyrrole pigment produced by several bacteria, most notably, Serratia marcescens.
灵菌红素有广谱的生物学活性,抗真菌、肿瘤细胞系和疟疾。
Prodigiosin has a broad biological profile with activity against fungi, tumor cell lines and malaria.
HPLC结果显示,灵菌红素的药理学作用与细胞内药物浓度相关。
The results of HPLC showed that pharmacological effect of prodigiosin dependent on drug concentration in cells.
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