我们推断糖尿病弱氟卡胺、 E-4031和维拉帕米的心律失常作用。

We concluded that diabetes mellitus reduces the antiarrhythmic effects of flecainide , E-4031, and verapamil.

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方法：以3-三氟甲基- 4- 氰基苯胺和2- 甲基丙烯酰氯为起始原料经过酰化、 环氧化、取代和氧化四步反应合成比卡鲁胺。

Methods:Bicalutamide was prepared from 4-cyano-3-(trifluoromethyl) aniline and 2-methylacryloyl chloride by four steps: acylation, cyclization, substitution, and oxidization.

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