毒扁豆碱（Physostigmine），别名依色林、卡拉巴豆碱、依色林，是一种白色、无味，微结晶样粉末的生物碱化学品。化学名称1,2,3,3A-六氢-1,3A,8-三甲基吡咯并[2,3-B]吲哚-5-酚甲基氨基甲酸酯，分子式为C15H21N3O2，分子量为275.34600，微溶于水，易溶于乙醇，极易溶于氯仿和二氯甲烷，溶于不挥发性油和苯，熔点102~104℃。毒扁豆碱为抗胆碱酯酶药，临床上主要有缩瞳、降低眼压作用。
n. eserine ; physostigmine
misc. calabarine
毒扁豆碱(Physostigmine)：毒扁豆碱是最早发现并用于临床的可逆性乙酰胆碱酯酶抑制剂，用于治疗青光眼，近年来也用于治抗胆碱药阿托品及三环类抗抑郁药中...
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水杨酸毒扁豆碱 [有化] Physostigmine Salicylate ; Salicylate eserine ; Eserine salicylate ; Physostigmini Salicylas
水杨酸毒扁豆碱眼膏 Physostigmine Salicylate Eye Ointment ; Physostigmine Eye Ointment
氧化毒扁豆碱 eserine oxide ; geneserine ; eseroline ; eseridine
水杨酸毒扁豆碱注射液 Physostigmine Salicylate Injection ; Physostigmine Salicylate Inj
硫酸毒扁豆碱 Eserine sulfate
异毒扁豆碱 isophysostigmine
毒扁豆碱盐酸盐 physostigmine hydrochloride
毒扁豆碱眼膏 Physostigmine eye oint
It has been demonstrated that TAK-147 is more potent and brain-specific AChE inhibition than tacrine and physostigmine, and has been approval potentiating choline acetyltransferase ( ChAT ) activity in cultured rat septal neurons more potent than donepezil, tacrine and revastigmine.
TAK－147与毒扁豆碱和他克林相比是具有更强作用和中枢选择性的胆碱酯酶抑制剂。 有报道表明，TAK－147对于培养的大鼠脊神经元具有比多奈派齐、他克林和 Revastigmine更强的提高ChAT活性的作用。
参考来源 - 乙酰胆碱脂酶抑制剂TAK·2,447,543篇论文数据，部分数据来源于NoteExpress
目的比较新斯的明、毒扁豆碱和毛果芸香碱对兔眼的缩瞳作用。
Objective To compare the myotic effects of physostigmine, pilocarpine and neostigmine in rabbits.
论新斯的明、毒扁豆碱和毛果芸香碱滴眼给药，均能缩小兔眼瞳孔，其时效关系相似。
Conclusion Physostigmine, neostigmine and pilocarpine, when applied locally to the eye in rabbits, could cause myosis and their time-effect relationships were comparable.
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