化学及生物学意义上的探针(probe),是指与特定的靶分子发生特异性相互作用,并可被特殊的方法探知的分子。抗体-抗原、生物素-抗生物素蛋白、生长因子-受体的相互作用都可以看作是探针与靶分子的相互作用。
61、 核酸探针(nucleic acid probe):探针是指能与某种大分子 发生特异性相互作用,并在相互作用之后可以检测出来的生物 大分子。
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...标记的核酸探针和未掺入的放射性游离单核苷酸,再经放射性强度测定即可计算出标记后的核酸探针的放射性比活。 nucleotide probe核酸探针
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核酸探针标记 label of nuclei acid probe
核酸探针杂配法 DNA probe hybridization
DIG标记核酸探针 DIG-labeled nucleic acid probe
寡核苷酸探针 Oligonucleotide probe ; allele-specific oligonucleotide
肽核酸探针 Peptide nucleic acid probe
荧光核酸探针 Fluorescent Nucleic Acid Probe
非放射性核酸探针 Nonradioactive nucleic acid probe
去氧核糖核酸探针 deoxyribonucleic acid probe
寡聚核苷酸探针 oligonucleotide probe ; TTTAGGG
The nucleic acid probe sensitivity and the specificity test result showed: This probe can examine the 1pg specificity nucleic acid, having high sensitivity and the specificity.
核酸探针敏感性和特异性试验结果显示:该探针能检测到1pg特异性核酸,具有很高的灵敏度和特异性。
参考来源 - 鸭群中REV感染的流行病学调查及囊膜糖蛋白基因的序列分析The PCR product was purified , quotaed and labeled by digoxin to prepare DNA probe.
PCR产物经测序验证无误后,回收、纯化、定量,用地高辛标记,制备出地高辛标记的核酸探针。
参考来源 - 鸭群中REV感染的流行病学调查及囊膜糖蛋白基因的序列分析The sensitivity result showed that as few as 1 pg DNA amount of CAV could be detected by DIG-labeled probe. So the DIG-labeled probe could be used to detect the CAV.
敏感性检测结果表明,该探针对CAV的最低检出量为1 pg核酸,具有较高的灵敏度,显示所制备的核酸探针用于临床病料组织DNA中CAV感染的检测是可行的。
参考来源 - 一株高致病性鸡传染性贫血病毒的生物学及基因组特性Then,the specificity and sensitivity of TK gene probe were detected with dot blot hybridization. The sequence of TK gene of NM98a strain was analysed.
采用斑点杂交的方法,对ILTV TK基因核酸探针进行特异性和敏感性检测。
参考来源 - 传染性喉气管炎病毒内蒙98a株TK基因的克隆、序列分析及核酸探针的研究The development of molecular biology and molecular pharmacology made it possible for people to comprehend some life phenomena;and to find sensitive nucleic acid probe and effective curative by molecular design.
分子生物学和分子药理学的发展使人们能够从基因水平理解某些生命现象,并通过分子设计来寻找灵敏的核酸探针和有效的治疗药物。
参考来源 - 生物小分子与DNA相互作用的光谱及二维核磁的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
结果表明,核酸探针是检测MDV灵敏特异的方法。
The results indicated that nucleic probe might be useful for the specific and sensitive assay of MDV.
本文介绍了核酸探针和制备技术,标记技术、核酸分子杂交方法及核酸探针的应用状况。
The nucleic acid probe, manufacture and labelling technology, hybrid method of nucleic acid molecule, and the current application status of nucleic acid probe were introduced in this paper.
该类配合物在分子识别、核酸探针、抗肿瘤药物、分子催化及自组装等领域都有广泛的应用前景。
The use foreground of these compounds will be extensive in the field of molecular discernment, nucleic acid probe, anti-tumour medicine, molecular catalysis and self-assemble etc.
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