已报道的包括转录因子、信号通路受体、黏附因子在内的ES细胞特异性标志与ES细胞的自我更新和全能性具有密切关系。
Es cell markers reported previously including transcription factors, receptors, adhesion molecules and so on, are involved in the mechanism of self-renew and differentiation initiation of es cells.
bmi1和wnt等信号信号通路在正常及肿瘤干细胞的自我更新中有类似的效果提示这一共同的分子途径可以调节两者的作用。
That signaling pathways such as Bmi1 and Wnt have similar effects in normal and cancer stem cell self-renewal suggests that common molecular pathways regulate both populations.
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