研究人员对1492名平均年龄为48岁的加拿大女性进行了跟踪调查。 她们携带的BRCA1和BRCA2两种乳腺癌易感基因都没有发生突变。
The study tracked 1,492 Canadian women with an average age of 48 who did not have mutations in either of two breast cancer susceptibility genes - BRCA1 and BRCA2.
但是,与因继承了乳腺癌易感基因1和乳腺癌易感基因2中的某些基因突变而增加了5倍风险相比,这种冒险是小得多的。
But it's far smaller than the fivefold increased risk that comes from inheriting certain mutations in the BRCA1 and BRCA2 genes.
结论AGT基因M 235t突变具有明显的遗传倾向,可能是汉族人群易患高血压的候选基因(遗传标志)。
Conclusion M235T variant of AGT gene may be the candidate gene (genetic marker) responsible for the genetic predisposition to EH in Chinese Han population.
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