Conclusions: 1. The rotational behavior of PD rats was significantly improved by VPlesion.2.
结论:1.VP 毁损术对 PD 大鼠的旋转行为有明显的改善作用。
参考来源 - 腹侧苍白球毁损术治疗帕金森病机制的实验研究·2,447,543篇论文数据,部分数据来源于NoteExpress
正常对照组、假手术组无旋转行为。
No rotary behavior appeared in the normal control group and sham operation group.
裸pc 12细胞移植组大鼠的旋转行为改善仅持续了2个月,且部分大鼠颅内有致死性肿瘤形成。
Although the unencapsulated PC12 cells could also improve the rotational behavior, the symptom improvement lasted only two months. In addition, several of the grafts developed into mortal tumor.
结论:大剂量左旋多巴干预能明显改善PD大鼠的旋转行为,并使纹状体多巴胺d2受体明显下调。
CONCLUSION: After high dose of L-dopa intervention, rotation behavior of PD rats improves, and D2 receptor is down-regulated significantly.
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