...新药筛选;药品评价 [gap=918]Key words] Metabolic syndrome; Animal model; Hyperlipemia; Hyperlipid diet; New drug screening; Drug evaluation ...
基于24个网页-相关网页
国家新药筛选中心 National Center for Drug Screening
Tissue microarray can be used to study the expression of gene and protein, and it has an important role in studying the expression of disease-related gene and protein, molecular diagnosis, evaluating the effect of treatment and screening of new drugs.
构建不同类型的组织芯片并以此研究基因和蛋白质表达情况,对人类后基因组学的研究与发展,尤其对于认识疾病相关的基因功能和蛋白质变化与分子诊断、评价治疗过程与效果、判断疾病预后以及新药筛选与开发等,都具有重要意义。
参考来源 - 人脑星形细胞肿瘤微血管(AstMV)组织芯片的构建与计算机辅助的AstMV三维重建·2,447,543篇论文数据,部分数据来源于NoteExpress
应用于抗肿瘤新药筛选;
目前该模型已用于以adrb3为靶点减肥新药筛选。
Currently, the model has been used for screening novel human ADRB3 agonists.
该活性片段经国家新药筛选中心确证有抑制单胺氧化酶的效果,具有潜在的抗衰老作用。
National Center for Drug Screening confirmed that the bioactive fraction was reliably inhibitory to monoamine oxidase and possessed potential anti-ageing effect.
Much of the work that pharmaceutical companies do in terms of searching for drugs is searching for new ligands that activate receptors and create biological responses inside cells.
很多制药公司新药筛选工作的主要内容,就是寻找能够激活受体的,新型配体,并在细胞内部产生某种生物学效应
应用推荐