阿司匹林药片治疗方法简便，效果却非常显著。

Aspirin is a simple but highly effective treatment.

《牛津词典》

实际上的效果却相反。

In reality, it had the opposite effect.

youdao

但是当产品搜结果出现时，效果却相当的不错。

Unfortunately, a lot of shopping searches I tried this morning didn't have Product Search results. When they are available, they are pretty good though.

youdao

Yeah, it's an anti-psychotic drug, some people with bipolar disorder even today still take it, it works really well for some people, for other people it doesn't work so well.

没错，它是一种用来治疗精神疾病的药物，患有躁郁症的人至今仍在用它来治疗，它对一部分人效果很好，但对其他人却不是这样。

麻省理工公开课 - 化学原理课程节选

You could tell your friend that you've tried it and it didn't work by using the "I've already" pattern.

你可以用“I've already”句型告诉你朋友，你已经用过了，却没什么效果。

I've already 课堂 - SpeakingMax英语口语达人