制备盐酸尼卡地平的凝胶骨架控释贴剂。
Nicardipine hydrochloride transdermal controlled release patches with gel matrix were prepared.
目的 研制格列美脲凝胶骨架控释贴剂，并评价其经皮吸收对正常大鼠的降血糖作用。
OBJECTIVE To prepare glimepiride gel-matrix controlled-release patch and to investigate its antihyperglycemic effects in normal rats after transdermal absorption.
结果表明，该聚氨酯压敏胶贴剂具有良好的药物控释能力，适用于经皮给药系统。
The results indicated that the hydrophilic polyurethane PSA prepared show good transdermal drug release properties, which suit for the TDDs application.
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