拉坦前列素是一种新型苯基替代的丙基酯前列素F2a,为选择性F2a受体激动剂。它是一种无活性但能迅速渗透到角膜里的物质,在角膜和血浆中可水解为具有活性的游离酸。它能增加房水通过眼角素层的流出量,用药量小,但促进房水充出量大,药液能渗透到眼球上睫脉络膜上层,具有良好降眼压效果。
拉坦前列素滴眼液 LatanoprostEyeDrops ; LatanoprostEye ; Latanoprost Ophthalmic Solution ; Latanopros
拉坦前列素杂质H latanoprost impurity H 15-Keto Latanoprost
拉坦前列素杂质A latanoprost impurity A trans-Latanoprost
拉坦前列素杂质E latanoprost impurity E Latanoprost Acid
拉坦前列素杂质C latanoprost impurity
拉坦前列素杂质F latanoprost impurity F 15-Keto Latanoprost
拉坦前列素杂质D latanoprost impurity D Latanoprost Tris Ether
拉坦前列素杂质B latanoprost impurity B -Latanoprost
拉坦前列素酸 human Tenon fibroblast
Latanoprost has the scalp hair growth promoting effect, which react on cultured follicles in the third to seventh day.
拉坦前列素对人头皮毛囊毛发生长亦有明显作用,其作用在培养的第3~7天显效。
参考来源 - 拉坦前列素对毛发生长影响的实验研究·2,447,543篇论文数据,部分数据来源于NoteExpress
目的:观察用降眼压药物而眼压不能控制的病人,加用拉坦前列素滴眼液治疗的临床疗效。
AIM: To observe the clinical effect of latanoprost eye drops in patients who intraocular pressure (IOP) was uncontrolled by decreases IOP drugs.
结论:对用降眼压药物而眼压不能控制的病人,加用拉坦前列素滴眼液可以有效的控制眼压,防止青光眼对视功能的进一步损伤。
CONCLUSION: by adding latanoprost can effectively control IOP in patients whose IOP was uncontrolled by decreases IOP drugs and prevent glaucoma from further damaging the visual function.
拉坦前列腺素增加了房水流畅度(67%),在给药1个小时内发生变化。而前列腺素e增加的房水流畅度较其少(13%)。
Latanoprost increased outflow facility (an increase of 67%), with changes occurring within 1 hour of receiving drug, whereas PGE caused less of a change in outflow (an increase of 13%) facility.
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