方法利用小鼠福尔马林试验和冰醋酸扭体试验,观察AMG的镇痛效果。
Methods The writhing test and the formalin test were performed in order to study the analgesic effect of AMG.
在扭体试验中,小鼠脑组织、血浆及腹腔灌洗液中MDA含量均有显著增高。
In the writhing test in mice, the MDA con tents in brain, plasma and peritoneal wash fluid also increased significantly.
方法通过醋酸扭体模型、热板、甩尾、纳洛酮拮抗试验及豚鼠回肠离体标本研究样品的镇痛活性及机制。
METHODS the writhing model of mice induced by acetic acid, hot plate test (sc, icv), tail flick test and the model of electrical stimulation induced contraction of guinea pig ileum were used.
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