扩张床吸附(Expanded Bed Adsorption,EPA)是流化床的一种特例。它具有流化床的特点,能处理含悬浮颗粒的液体。又具有固定床的优点,流动成活塞流,返混程度低,分离效率高。作为蛋白质的初步分离方法,他能够取代固液分离、浓缩和初步纯化等三步操作。具有提高效率、降低投资费用、缩短操作时间等有点,成为生物下游工程中的研究热点。
扩张床吸附技术 expanded bed adsorption ; EBA
Mixed-mode adsorption is a novel bioseparation technique, which is especially suitable for expanded bed adsorption (EBA) to directly capture of target protein from moderate ionic strength feedstock without the need of dilution or other additives.
混合模式吸附技术是一种新型的生化分离技术,配基兼有离子交换功能和疏水相互作用,可以从中等离子强度的料液中直接捕获目标产物,避免对料液的预处理,比如稀释、加盐等步骤,从而有望提高分离效率,特别适合于扩张床吸附初分离的要求。
参考来源 - 混合模式扩张床吸附剂的制备及其用于蛋白质分离的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
该分离过程充分体现了扩张床吸附的集成化优势和新型混合模式扩张床吸附剂的优良性能。
The separation process demonstrated the integration advantage of expanded bed adsorption and the excellent properties of the novel mixed-mode expanded bed adsorbent.
第一部分集中综述了扩张床吸附剂基质的研究进展,包括基质所需要的理化性质、常见的扩张床基质和它们的制备方法。
The focus of Section 1 is the review of advances in matrices for EBA, including physicochemical properties required, matrices in use as well as their preparation methods.
此外,还建立了一系列表征所制备的扩张床基质和吸附剂的方法。
Furthermore, a series of methods for analysis and characterization of the prepared matrix or adsorbent were established.
应用推荐