用小型的、自动机技术针对靶蛋白、细胞或组织筛选大量化合物文库以识别潜在新药。
The use of miniaturized, robotics-based technology to screen large compound libraries against an isolated target protein, cell or tissue in order to identify binders that may be potential new drugs.
此外,组蛋白乙酰转移酶的活性对HIV的增殖是必要的,至少一个科学小组建议组蛋白乙酰转移酶或相似的酶做为靶点也许是抑制病毒一个新方式。
In addition, hat activity is necessary for the multiplication of HIV, leading at least one scientific group to suggest that targeting HATs or similar enzymes might be an new way to thwart the virus.
此复合体中P23作为HSP90的伴侣分子,能够和HSP90特异性结合,调节HSP90与ATP或ADP结合的形式而达到结合或释放靶蛋白的功能。
P23, as one co-chaperone of HSP90, could bind to HSP90 specially, let HSP90 bind or release the target protein by regulating the form of the HSP90 binding with ATP or ADP.
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