肿瘤细胞的MRP表达量明显增加，说明胃肠道肿瘤存在较高的原发性耐药(intrinsic drug resistance)，MRP检测有助于临床化疗药物的选择.
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天性耐药(intrinsic resistance)即在治疗开始时就表现 出对药物的高度耐受性和获得性耐药( a c q u i r e d
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获得性耐药 acquired resistance ; acquired drug resistance ; acquired bacterial drug resistance
继发性耐药 secondary resistance ; secondary drug resistance
原发性耐药 Primary resistance
血管性耐药 vascular tolerance
适应性耐药 adaptive resistance
补偿性耐药变异 compensatory resistance mutation
原发性耐药变异 primary drug resistance mutation
交叉性耐药 cross-tolerance
异质性耐药 heteroresistance
医院感染与细菌性耐药密切相关。造成细菌性耐药的因素众多。
There are very intimate relationships between nosocomial infection and bacterial resistance.
很多监测研究证明的高敏感性，个别报告有医院获得性耐药株。
While most surveillance studies demonstrated high rates of susceptibility, several reports noted the emergence of polymyxin-resistant nosocomial pathogens.
目的：评价头孢西丁扩散法检测耐甲氧西林葡萄球菌异质性耐药菌株的可靠性和临床实用性。
Objective To evaluate the reliability and clinical practicability of cefoxitin disk diffusion test in the detection of methicillin-resistant staphylococcus (MRS) heterogenic drug-resistant strains.
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