目的探讨同系或同种胸腺与异种胸腺混合移植防止器官特异性自身免疫损害的可行性。
Objective to explore feasibility of prevention of organ specific autoimmune disease by transplanting mixed fetal syngeneic or allogeneic and xenogeneic thymus.
结论:异种血管内皮生长因子基因重组T7噬菌体疫苗可打破机体对自身vegf的免疫耐受,诱导产生较高水平的特异性抗vegf抗体。
Conclusion: Recombinant T7 phage vaccine expressing xenogenic VEGF can break immunologic tolerance against self-VEGF and induce the producing of specific anti-VEGF antibody.
本发明涉及一种制备异多聚体多肽如双特异性抗体、双特异性免疫粘附素和抗体—免疫粘附素嵌合体的方法。
The invention relates to a method of preparing heteromultimeric polypeptides such as bispecific antibodies, bispecific immunoadhesins and antibody-immunoadhesin chimeras.
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