请你先开个头。

Would you make a start?

《新英汉大辞典》

我猜想最好自愿去唱第一首歌开个头。

I guess I'd better volunteer to sing the first song.

youdao

他们明天所要讨论的问题是：哪一组先开个头。

It is which group is to have the first move that they will discuss tomorrow.

youdao

We don't really have a clue yet, or not much of a clue, as to how you could even so much as begin to-- it's not that merely that we don't have the details worked out.

毫无头绪,或者说,无从下手,你如何在这种情形下开个头,我们不只是不知道细节如何

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