...ejection,HAR)、急性血管性排斥反应,acute vascular rejection,)或称延迟性排斥反应(delayed xenograft rejection ,DXR)和细胞介导的排斥反应。
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目的建立一个简便的研究延迟性排斥反应的猪—猴异种心脏移植模型。
Objective to establish a simple pig-to-monkey xenograft model to study delayed xenograft rejection (DXR).
在豚鼠—大鼠异种心脏移植中,给以眼镜蛇毒因子以避免发生超急性排斥反应,制作延迟性排斥反应模型。
In guinea pig to rat heart xenotransplantation model, cobra venom factor is administrated to avoid hyperacute rejection, and thus delayed xenograft rejection model is made.
结论异种移植发生延迟性排斥反应时,P选择素和ICAM - 1均有表达,可以作为判断异种移植免疫抑制治疗效果的指标之一。
Conclusion the expression of P-selectin and ICAM-1 in xenografts was increased during delayed xenograft rejection, which is of value in judging the effect of immunosuppression in xenotransplantation.
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