研究壳聚糖对豚鼠单一心室肌细胞延迟外向钾电流(I_k)的作用,从离子通道角度初步探讨其作用机理。
To study the effect of chitosan on delayed outward potassium current(IK) in single ventricular myocytes of guinea pig and investigate its antiarrhythmic mechanism from ion channel view.
结论:卡托普利具有的电生理作用是由于它降低外向延迟整流钾电流及延长APD30、APD50和ERP。
CONCLUSION: Captopril exerts electrophysiologic action due to decreasing delay outward rectification potassium current and prolonging action potential duration of APD30, APD50 and ERP.
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