庆大霉素的峰值浓度和浓度梯度在动物之间的差异相当的大,这可能是由圆窗膜通透性的不同和外淋巴液流动率的不同所导致的。
Peak concentrations and gradients for gentamicin varied considerably between animals, likely resulting from variations in round window membrane permeability and rates of perilymph flow.
结果表阿霉素在术后早期腹腔内化疗时腹腔液峰值浓度比外周静脉高228倍,且持续时间长;腹腔液总平均浓度比外周静脉高167倍。
Results: the peak and the mean levels of epirubicin in the peritoneal fluid were 228 and 167 times higher than the corresponding peripheral vein levels.
我们没有观察到利培酮合用锂盐或丙戊酸钠的不良反应,尽管在丙戊酸钠上血浆浓度峰值增加20%。
No effects of risperidone on lithium or valproate exposure were observed, despite a 20% increase in valproate peak plasma concentration.
Those levels would reach a plateau after some period of time, maybe after a couple of weeks and then they would begin to decline again.
在一段时间后,抗体浓度将达到峰值,峰值大约出现在几周之后,之后,抗体浓度将开始下降
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