目的：探讨稳态层流下的内皮细胞特征变化规律和血流切应力改变对血管内膜结构的影响。
Objective: to study the regular rule of changes in endothelial cells morphometric feature under steady flow state, and to investigate the effects of shear stress on the structure of vascular intima.
由于低渗透页岩地层流体高温膨胀导致的超孔隙压力，有可能产生有效拉张应力，严重时会导致地层破裂。
Due to the higher thermal expansion of fluid in low permeability shale, the super pore pressure may lead to the development of effective tensile stress and even formation fracturing.
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