尼群地平,用于冠心病及高血压,尤其是患有这两种疾病的患者,也可用于充血性心力衰竭。
...ide Dinitrate)也称消心痛;硝苯地平(Nifedipine)也称硝苯吡啶、心痛定;尼卡地平(Nicardipine);尼群地平(Nitrendipine);尼莫地平(Nimodipine);尼尔硫卓(Diltizem)也称硫氮卓酮。
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Conclusion Tianmagouteng decoction can improve endothelial dysfunction by increasing serum NO and decreasing serum ET-1. Tianmagouteng decoction have same efficacy in lowering the clinic blood pressure compared with Nitrendipine.
结论 天麻钩藤饮可以升高患者血清NO,降低血清ET-1水平,从而改善原发性高血压患者受损的血管内皮功能;天麻钩藤饮还具有尼群地平同样的降压效果和比尼群地平更高的改善症状疗效作用。
参考来源 - 天麻钩藤饮对原发性高血压(肝阳上亢证)患者临床疗效及对血管内皮功能的影响The results showed that nitrendipine has high solubility in 0.5% Sodium dodecyl sulfate solution, but almost insolvable in water, the solubility is 2.14×10-3mg/ml.
结果发现,尼群地平在0.5%十二烷基硫酸钠溶液中具有最大溶解度为5.333mg/ml,在水中几乎不溶,为2.14×10-3mg/ml。
参考来源 - 尼群地平控释片的制备及质量评价·2,447,543篇论文数据,部分数据来源于NoteExpress
目的:提高尼群地平的体外溶出速率。
Objective:To improve the dissolution of nitrendipine preparation.
尼群地平虽也有此作用,但较雷米普利弱。
Nitrendipine also could restrain sympathetic nervous activity, but the role was weak than ramipril.
结论健康志愿者对复方尼群地平片能较好耐受。
Conclusion The tolerance of compound nitrendipine is good in healthy volunteers.
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