药物对映体结构特异性对局麻药药代动力学的各个过程都有着很大影响，包括药物的吸收、蛋白结合率、代谢等。
The enantiomer-specific structure of local anaesthetics has large impact on the pharmacokinetic process of these drugs, including absorption, protein-binding ratio, metabolism, and so on.
考察了流动相组成、溶质结构和柱温对对映体分离的影响，并初步探讨了手性识别的机理。
The effects of composition of mobile phase, the structure of solute and the column temperature on chiral separation were extensively studied. The chiral recognition mechanism was discussed.
计算结果表明所制得的痂囊腔菌素A是一种新的光学活性对映体，由此推测痂囊腔菌素A的高光敏活性可能与手性结构特征有关。
The calculation results show that the EA is a new optical stereoisomer and whose great photosensitivity could be related to the chirality of EA molecules.
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