对于大多数患者来说，在童年视力就开始失去。
For most sufferers, vision begins failing in early childhood.
然而，对于大多数患者，高能机制导致高比率的多发伤。
However, for the majority, the high energy mechanism results in a high rate of associated injuries.
不管最近刚刚获批的晚期RCC的新治疗法如何，大多数对于正在进行的治疗无响应的患者都有着不良的预后。
Despite the recent approval of new therapies for advanced RCC, many patients who do not respond to the existing treatments have a poor prognosis.
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