很多使胚胎发生破坏或者丢失染色体而导致流产，但有一些则出现如唐氏综合征这样的状况！
Many embryos that have damaged or missing chromosomes miscarry, but others go on to produce conditions such as Down's syndrome.
我们希望并期待其他发育障碍，如x染色体脆弱症。 老鼠试验能够帮助进行对有益于病人的临床试验。
We hope and expect that, like other developmental disorders such as Fragile X syndrome, the use of mouse models will lead directly to clinical trials that can benefit patients.
如果调控紊乱，则基因组畸变累积，如重复的DNA序列甚至出现整条多余的染色体。
When regulation fails, genome aberrations accumulate, including repeated sequences of DNA or een entire extra chromosomes.
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