探讨利用基因枪技术转移肝细胞生长因子基因治疗大鼠肢体闭塞性血管病的可行性。

To explore the feasibility of gene therapy with hepatocyte growth factor (HGF) transferred using gene gun technique in treatment of peripheral vascular disease of rat limb.

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结论肝细胞生长因子能显著促进大鼠减体积肝移植术后肝组织的再生，而对术后肝脏功能无明显损害作用。

Conclusion HGF improved liver regeneration after reduced-size liver transplantation in rats and has no negative effects on liver function.

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利用肝细胞生长因子促进血管生成的作用，采用质粒作为载体对大鼠和犬的下肢动脉闭塞疾病模型进行治疗，效果良好。

We used the angiogenesis effect of hepatocyte growth factor to treat the PAD and found the growth of new vessels.

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