大换血，读作dàhuànxuè，汉语词语，是指更换人体血液来治疗某些疾病，对组织机构的人员进行大的调整和更换。
沙尔克04本赛季对球队实行了 大换血 ( Exchange transfusion )，球队引进了不少有实力的球员，只是球队的磨合(Running)是一大问题。你曾经恨过一个人吗？
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这一季的美国偶像经历了一次评委大换血。
So much has been made of the chemistry among the judges this season on American Idol.
刚刚练习完投篮，准备迎战大换血后的尼克斯队。
Just finished shoot around and preparing for the new look Knicks.
新界面的研发处于极度保密中，只有开发的少数人知道它进行了大换血。
The interface was designed in intense secrecy. Only the handful of people working on it knew it was being overhauled.
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