离断大鼠左侧坐骨神经作为外周神经损伤模型，右侧作为对照，在离断处移植NT-4基因修饰细胞。
The rats with left sciatic nerve apocoped were taken as model for treatment by implanting NT 4 genetically modified cells.
包括新生时期在内的胞外信号会影响染色体的修饰，从而调控和代谢相关的基因表达，进而影响到我们代谢综合征的易感性。
Chromatin modifications in response to extracellular cues, including during early life, regulate metabolic gene expression and may contribute to metabolic disease susceptibility.
在一些实施方案中，可以用基因构建体转染这些PGC，以修饰所述pgc的DNA，特别是引入编码外源蛋白质的转基因。
In some embodiments, these PGCs can be transfected with genetic constructs to modify the DNA of the PGC, specifically to introduce a transgene encoding an exogenous protein.
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