四君子汤,是人参、白术、茯苓、甘草四味基本中草药为主的古方剂,主治脾胃气虚。该方为治疗脾胃气虚证的基础方,後世众多补脾益气方剂多从此方衍化而来。临床应用以面白食少,气短乏力,舌淡苔白,脉虚弱为辨证要点。四君子汤是从《伤寒论》中的“理中丸”脱胎,把原方中秉性燥烈的干姜去掉,换成了性质平和的茯苓,由驱除大寒变成温补中气。方中只人参、白术、茯苓、甘草四味,不热不燥,适度施力,从了“君子致中和”的古意。 四君子汤是著名古方剂,也因此有专门介绍的同名图书出版。
Objective: To optimize the conditions of extraction for polysaccharide of Sijunzi Decoction.
目的:研究四君子汤总多糖提取的最佳工艺条件。
参考来源 - 四君子汤总多糖的提取研究—《中国医药导报》—2009年第14期—龙源期刊网Compared with model group,Sijunzi Soup NOS in rat penile tissue were significantly increased(P<0.05).
与模型组比较,四君子汤大鼠阴茎组织NOS含量明显增加(P<0.05)。
参考来源 - 脾气虚对雄性大鼠性功能影响的实验研究V. The influence of the Decoction of Four Noble Drugs on telemeter enzyme activity of the tissues of the heart, brain, liver and thymus gland of the mice in the D-gal aging model.
5、四君子汤能明显提高D一gal衰老模型小鼠脑及胸腺组织端粒酶活性;对心脏组织端粒酶活性有提高的趋势,但作用不显著;而对肝脏组织端粒酶活性没有影响。
参考来源 - 四君子汤对DThe datas of the drug concentration-time inthe two groups of the Healthy group, Spleen deficiency groupwere fittedto a one- compartment model with first-order absorption, the counterparters of Sijunzi decoction antisyndrome group were in line with a two-compartment with first-order absorption.
健康组和脾虚组的药时数据符合一级吸收一室模型,四君子汤反证组药时数据符合一级吸收二室模型。
参考来源 - 脾虚仔猪单剂量内服左旋氧氟沙星的“辨证药动学”研究Conclusions(1)Sijunzi formula can cooperate with exercise training to prolong swimming time exhaustion of rats,there is a obvious effect of sijunzi formula on increasing exercise ability and resisting fatigue.
结论:1.四君子汤能够辅助运动训练显著延长小鼠游泳的力竭时间,具有明显的提高机体运动能力和抗疲劳能力的作用。
参考来源 - 四君子汤对训练小鼠血清和肝脏自由基变化影响的实验研究·2,447,543篇论文数据,部分数据来源于NoteExpress
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