喹乙醇(olaquindox)又名倍育诺、快育灵等,是淡黄色结晶状粉末。其抗菌效果优良，对革兰阴性菌特别敏感，对革兰氏阳性菌的最小抑菌浓度为50~100μg/ml,优于金毒素等。对螺旋体也有抑制作用，另外对其它抗生素有耐药性的细菌,对喹乙醇仍很敏感。喹乙醇的化学合成法生产，是以邻硝基苯胺为原料，首先与次氯酸钠反应生成苯氧二氨茂。N-氧化物，再与双乙烯酮、乙醇胺反应制得喹乙醇，粗品可经重结晶而精制。
The number of microflora reduced markedly in fore-gut from dose of 1600 mg-kg-1, in mid-gut from dose of-IV-200 mg-kg’1, in hind-gut at all olaquindox-treated group.
从1600 mg·kg-1剂量起，前肠细菌数量明显下降，从200mg·kg-1起中肠的细菌数量开始下降，后肠中的细菌数量在各个喹乙醇处理组中均呈下降趋势。
参考来源 - 喹乙醇对鲤鱼的生理生化效应及其在组织中的残留This study presented a liquid chromatography-tandam mass spectrometry(LC-MS/MS) method for determination of residues of Carbadox,Olaquindox and related metabolites quinoxalie-2-carboxylic acid(QCA) and 3-methylquinoxaline-2-carboxylic acid(MQCA) in milk and milk powder.
建立了牛奶和奶粉中卡巴氧代谢物喹喔啉-2-羧酸（QCA）和喹乙醇代谢物3-甲基喹喔啉-2-羧酸（MQCA）残留量的液相色谱-串联质谱测定方法。
参考来源 - 液相色谱·2,447,543篇论文数据，部分数据来源于NoteExpress
喹乙醇对草鱼肝细胞和胰腺外分泌部细胞的毒理研究。
Toxicological effect of olaquindox on liver cells and pancreas exocrine cells of Ctenopharyngodon idellus.
本文介绍了用高效液相色谱测定配合饲料添加剂中喹乙醇含量的方法。
A method of HPLC which was simple, rapid, sensitive and accurate for determining the amount of olaquindox in complex feed additive was reported.
本实验研究了喹乙醇饲料添加剂的生物代谢物3-甲基-喹啉-2-羧酸的制备方法所制备的产品。
This study was to synthesis a metabolite of additive of Olaquindox named methyl-3-quinoxaline-2-carboxylic acid.
应用推荐