突变致癌学说将化学致癌过程分为启动(initiation)、促进(promotion)和演变(progression)3个阶段。 启动阶段是致癌物直接作用于DNA初级序列,引起基因突变,使多个或少量细胞发生功能永久性的、不可逆的遗传性改变。具有这种作用的物质成为启动剂(initiator)。
结论桦木尘提取液可能为一启动剂,桦木尘水提取液的致癌性强于有机提取液。
Conclusion Both extracts of birch wood dust may be initiators, and carcinogenic effect of the water extract is stronger than that of the organic extract.
结论CSS和CH单独作用均为肿瘤启动剂;当二者联合作用时可协同启动肿瘤的发生。
Conclusion Both CSS and CH may act as initiator in carcinogenesis, and may synergistically initiate tumors when CSS and CH were exposed simultaneously.
对于还没有企业数据质量计划的组织,这可能是启动一个企业数据质量计划的催化剂。
This may be a catalyst for initiating an enterprise data quality initiative in the organization if one does not already exist.
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