方法用计算机同源模建预测多肽的抗原性,然后用淋巴细胞转化试验验证其抗原性。
Methods the antigenicity of the synthetic peptide were predicted by the computer modeling, then verified by lymphocyte transformation test.
利用同源模建的方法,借助分子力学优化、分子动力学模拟退火设计构建了删除部分氨基酸序列的蓖麻毒素A链突变体(MRTA)。
Using homology method, mutant ricin toxin A-chain(MRTA) deleting part of amino acid sequence was modeled by molecular mechanics optimization and molecular dynamics simulated annealing.
结论同源模建是一种高效寻找具有保护性的抗原多肽的经济快速的方法。
Conclusions the computer homogeneity modeling is an economic mean by which the protective peptide can be found out quickly.
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