除了诱导耐受的经典途径外,免疫学家已认识到还有其他方法调节或终止免疫应答,其中口服耐受(oral tolerance)就是较好的途径。这些途径涉及诱导产生调节T细胞群体,为此这种处理被定名为负疫苗的作用。
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DCs, as an initiator of immune response, may play a secondary role in the mechanism of oral tolerance.
DCS作为免疫反应的始动者,其数量变化在口服耐受的产生机制中起着一种次要作用。
参考来源 - 树突状细胞在实验性变态反应性脑脊髓炎发病和耐受中作用的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
目的:探讨免疫性流产口服耐受疗法的可行性。
Objective: to study feasibility of oral tolerance therapy to immune abortion.
结果:与对照组相比较,口服耐受组大鼠DTH和抗原特异性淋巴细胞增殖反应明显受抑制;
RESULTS: In comparison with control group, the DTH and antigen specific lymphocyte proliferation reaction in oral tolerance group were suppressed significantly;
目的:利用口服供者脾细胞延长受者大鼠的心脏移植存活时间,并探讨口服耐受的形成机制。
Objective To induce the prolongation of survival period of heart allografts in recipient rats by oral administration of donor spleen cells, and to study the mechanism of oral tolerization.
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