这个事实告诉我们,家族基因中,除了HLA-B27基因以外,还有其他的基因,我们可以称之为发病基因(Susceptbility gene)。这个发病基因与B27共同存在时,可以增加强直性脊柱炎的发病率,不过,目前仍不知道这个发病基因位在那个染色体上。
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该病属常染色体隐性遗传,与X-染色体关联,所以,母亲是基因携带者的男性表现为发病。
The disease is autosomal-recessive and linked to the X-chromosome, so that men whose mothers are carriers of the gene manifest the disease.
一项12国联合研究表明,自闭症的发病与特定关键基因异常存在关联。
Key genetic abnormalities linked to autism have been identified in research by scientists from 12 countries.
导致乳腺癌与直肠癌的变异基因截然不同也就说明这两种癌症的发病机制有着很大的差异。
The mutated genes in breast cancers and colorectal cancers were almost completely distinct, suggesting the two cancers develop along different pathways.
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