同时，组织蛋白的去乙醯化（histone deacetylation） 也被认为会借由染色体结构重组而抑制基因的表现，所以我们也一并进行分析， 观察UK114 之表现是否受其调控。
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组蛋白去乙酰化酶 HDAC ; histone deacetylase ; histone deacetylases HDACs ; hi stone deacetyltransferases
去乙酰化酶 Sirtuin ; HDAC ; histone deacetylase ; Sirtl
芳乙酰胺去乙酰化酶 AADAC
组蛋白去乙酰化 Histone Deacetylation
组织蛋白去乙酰化酶 HD
去乙酰化酶抑制剂 histone deacetylase inhibitor HDACi ; HDACI
人组织蛋白去乙酰化酶 Human HD ; Human Histone Deacetylase ELISA KitELISA ; HD ELISA Kit
白去乙酰化酶 histone deacetylase ; HDAC
芳乙酰铵去乙酰化酶 AADAC
SIRT1 and AMPK are energy receptors in cells,regulating the activity of PGC-1α by means of phosphorylation and deacetylation.
SIRT1和AMPK(腺苷酸活化蛋白激酶)是细胞内的能量感受器,通过磷酸化、去乙酰化调节着PGC-1α的活性。
参考来源 - 运动对胰岛素抵抗骨骼肌AMPK/SIRT1/PGCTumorigenesis is always accompanied by the epigenetic modifications of anti-oncogenes,such as DNA methylation and histone deacetylation.
肿瘤发生过程中,经常伴有抑癌基因的表观遗传学修饰,如DNA甲基化、组蛋白去乙酰化等。
参考来源 - 硫氧还蛋白结合蛋白·2,447,543篇论文数据，部分数据来源于NoteExpress
靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。
Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.
通过在位于顾客蛋白结合区该位点制造突变，可模拟乙酰化或者去乙酰化氨基酸。
Mutations were made at this site, which is located in a region where client proteins bind, to mimic either an acetylated or a non-acetylated amino acid.
组蛋白乙酰化和去乙酰化可调节染色体的多种功能，例如基因表达和染色体分离等。
Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.
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