...化模型大鼠肾组织中基质金属蛋白酶组织抑制剂-1(TIMP-1)表达的影响,及其对肾间质纤维化的作用机理。方法:采用单侧输尿管结扎(UUO)致肾间质纤维化的动物模型,以目前公认具有肾脏保护作用的血管紧张素转换酶抑制剂(ACEI)作为阳性对照,将40只雄性Wistar大鼠(体重为...
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本研究通过对大鼠进行单侧输尿管结扎(unilateral ureteral obstruction，UUO)，建立肾间质纤维化模型，动态观察苦参素对梗阻侧肾脏的病理改变及生化指标的影响，用RT-PCR法测定梗...
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迄今为止,国内外尚未见促肝细胞生长素对单侧输尿管结扎(unilateral ureteral occlusion,UUO)大鼠模型肾组织HGF、TGF-β1、ALK5表达影响的研究。
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单侧输尿管结扎术 unilateral ureteral obstruction ; UUO
大鼠单侧输尿管结扎 unilateral ureteral obstruction ; UUO
对单侧输尿管结扎 Unilateral Ureteral Obstruction ; unilateral ureteral occlusion ; UUO
采用单侧输尿管结扎 unilateral ureteral obstructive ; UUO
红花对单侧输尿管结扎 unilateral ureteral obstruction ; UUO
采用单侧输尿管结扎术 unilateral ureteral obstruction
验采用单侧输尿管结扎 unilateral ureteral obstruction
鼠单侧输尿管结扎术 unilateral ureteral obstruction
用单侧输尿管结扎术 unilateral ureteral obstruction
方法：将大鼠随机分为单侧输尿管结扎试验组和假手术对照组。
METHODS: The rats were randomly divided into unilateral ureteral ligation Testing Group and sham operation Control Group.
目的：探讨中药抗纤灵方对大鼠单侧输尿管结扎(UUO)所致肾纤维化的防治作用及机制。
Objective: To study the effects of "Kangxian Ling Decoction" (KLD) on renal interstitial fibrosis induced by unilateral ureteral obstruction (UUO) in rats.
例如，ED5可以减少小鼠尿路梗阻（单侧输尿管结扎）或通过电穿孔法切除肾脏7天后皮质早期生长反应基因-1信使RNA表达和间质纤维化。
For example, ED5 reduces cortical Egr-1 mRNA expression and interstitial fibrosis in rats 7 days after renal obstruction (unilateral ureteral ligation) and delivery by electroporation.
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