正在进行以添加第三种药物的研究，即静脉注射的前列腺素类花青素。

Studies are underway investigating the addition of a third agent, the intravenous prostanoid epoprostenol.

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对于病人来说，疾病还没有得到良好的控制，目前正在进行有关第三种药物即静脉前列腺素类依前列醇的研究。

For patients whose disease is still not well-controlled, studies are underway investigating the addition of a third agent, the intravenous prostanoid epoprostenol.

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一种可能的选择是米索前列醇的标示外使用，这是一种合成的前列腺素E1类似物，被核准用于防止和治疗胃肠道溃疡。

One possible option in this setting is the off-label use of misoprostol, a synthetic prostaglandin E1 analogue licensed for prevention and treatment of gastrointestinal ulcers.

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