结论：异烟肼和利福平联用氧氟沙星肝毒性增加，但并不比异烟肼和利福平联合时强。
Conclusion: combination ofloxacin with isoniazid and rifampicin in mice increase hepatic toxic injury, but the level of injury was little lower than combination isoniazid with rifampicin.
前言：目的：探讨n乙酰基转移酶(NAT2)基因型与异烟肼、利福平治疗肺结核致肝毒性的相关性。
Objective: to investigate the relationship between the susceptibility of isoniazid and rifampicin-induced hepatotoxicity and the N-acetyltransferase 2 (NAT2) genotype in the tuberculosis patients.
目的：利用基因芯片技术研究抗结核病药物利福平对大鼠肝脏毒性效应的分子机制。
Objective: To investigate the gene expression profiles of rat liver tissue injured by rifampicin (RFP) using cDNA microarrays.
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