集装箱作为运输的主要载体，其合理设计和安全操作成为决定运输成败的关键因素。
As the main equipment, reasonable design and safety operation of containers have become key factors to the success of the transportation.
合理化药物设计利用靶分子和其结合分子的高分辩率结构。
Rational drug design (also known as structure-based drug design) uses the high-resolution (atomic) structure of the target molecule, and of molecules that bind to it.
其次，由于信息量过大和其不合理的设计，网页的可读性大大降低。
Secondly, the pages are difficult to read because of both the design and the amount of information on the pages. Most of the information is not needed and will not enhance transactions.
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