考虑到各种因素，你最好离开。

Taking everything into consideration, you should leave.

youdao

他不是好人，你最好离开他。

He is not a good guy. You'd better brush him off.

youdao

你最好离开英国到比较暖和的国家去住。

You'd better quit England and live in a warmer country.

youdao

If I want to persuade you that I love you, would never leave you, you can trust me with everything, it may be a superb tactic for me to believe it.

如果我想让你相信我爱你，永远都不离开你，你什么都可以信任我，或许最好的策略便是我自己对此深信不疑。

耶鲁公开课 - 心理学导论课程节选

But even then if you are mugged, the best thing is to give them your belongings and leave.

但如果你遭遇抢劫，最好的办法就是把你的财物都给他们，然后离开。

大城市是否危险？ - SpeakingMax英语口语达人