【Key words】 Pichia pastoris； recombinant human serum albumin (rHSA)； model predictive control； productivity optimising；
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采用正交试验法，在优化的条件下苊烯产率达59.09%。
Orthogonal test method was used to optimize reaction conditions and the yield of acenaphthylene reached 59.09%.
优化条件下，硬脂酸丁酯的产率97%以上。
In the optimal condition, the yield of butyl stearate was over 97%.
对反应时间、温度和催化剂用量加以优化，反应产率达到95%。
The reaction parameters such as reaction temperature, reaction time and catalyst dosage were optimized and 95% of Z-Asn-OBut were obtained.
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