二磷酸腺苷钙为蛋白激酶激活剂,可同时激活蛋白激酶A和蛋白激酶C(cAMP仅激活蛋白激酶A),蛋白激酶是一种别构酶,由两个催化亚基和两个调节亚基组成,催化亚基具有催化蛋白质(或酶)磷酸化作用。
目的观察二丁酰环磷腺苷钙扩张型心肌病心力衰竭的疗效。
Objective To assess the therapeutic effect of calcium dibutyryladenosine cyclophosphate on heart failure in patients with dilated cardiomyopathy (DCM).
方法将106例患者随机分为两组,在常规抗心力衰竭基础上,渝疗组加用二丁酰环磷腺苷钙静脉给药;
Methods A total of 106 DCM patients with heart failure were allotted into trial group and control group at random.
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